Prognostic factors affecting smoking cessation A real-life study in a population of Greek smokers visited a smoking cessation clinic
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Respiratory Failure Unit, "George Papanikolaou" General Hospital of Thessaloniki, Aristotle’s University of Thessaloniki, Thessaloniki, Greece
A.U.TH. Pulmonary Clinic, "George Papanikolaou" General Hospital of Thessaloniki, Aristotle’s University of Thessaloniki, Thessaloniki, Greece
Corresponding author
Serafeim-Chrysovalantis Kotoulas   

42–44 Sarantaporou street, 54639 Thessaloniki, Greece
Pneumon 2019;32(1-2):12-22
Smoking is a chronic disease not only responsible for numerous premature deaths every year, but also for substantial financial burden on health systems. Greece is still one of the leading countries in European Union (EU) in prevalence and incidence of smoking, a fact leading to even higher rates of morbidity and mortality and increases the cost of healthcare. The aim of this study is to identify predictors which play a role in a successful smoking cessation effort in three and six months, in Greek patients, who visited a smoking cessation clinic.

The research designed as a "case – control" study. Participants were patients who visited the smoking cessation clinic and agreed to take part in the research, answered all the questions needed and could be re-evaluated after three and six months. Out of 231 patients who visited the clinic during a year, 100 fulfilled the above criteria and were divided into two groups; those who succeeded in smoking cessation and those who failed; Fagerström (FNDT), Minnesota (MNWS) and Rosenberg questionnaires, along with questions about epidemiologic and other features were used to evaluate the patients. Multivariate regression analysis was performed to identify predictors which played a role in successful smoking cessation.

Among various characteristics examined, multivariate regression analysis indicated that "difficulty in concentration" of the MNWS as well as the whole score of MNWS and FNDT and the reduced number of cigarettes after work independently predicted smoking cessation.

This research confirms that the answers of smokers in both MNWS and FNDT should be taken under consideration for personalized medicine in smoking cessation treatment. Moreover, smoking cessation programs at workplaces should be implemented, because it seems that the increased number of cigarettes at work associates with higher smoking cessation success rates.

aOR: adjusted Odds Ratio, Backward LR: Backward Likelihood Ratio, BMI: Body Mass Index, EU: European Union, FEV1: Forced Expiratory Volume in 1 second, FNDT: Fagerström Nicotine Dependence Test, MNWS: Minnesota Nicotine Withdrawal Scale, NRT: Nicotine Replacement Therapy, OR: Odds Ratio, RS: Rosenberg self-esteem scale, SD: standard deviation, WHO: World Health Organization
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
This paper was not funded.
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