What is the truth about Electronic Cigarettes?
More details
Hide details
Lecturer of Respiratory Medicine, Aristotle University of Thessaloniki, Respiratory Failure Unit, G. Papanikolaou Hospital, Exohi, Thessaloniki, Greece
Professor of Lecturer of Respiratory Medicine, Aristotle University of Thessaloniki, Respiratory Failure Unit, G. Papanikolaou Hospital, Exohi, Thessaloniki, Greece
Corresponding author
Athanasia Pataka   

Respiratory Medicine, Medical School, Aristotle University of Thessaloniki Respiratory Failure Unit, G. Papanikolaou Hospital, 57010 Exohi, Thessaloniki, Greece
Pneumon 2012;25(3):272-275
Cigarette smoking is the leading preventable cause of mortality. Every year many smokers try to stop smoking, but this is difficult as nicotine is a psychoactive agent that causes dependence and tolerance. The electronic cigarette or e-cigarette was recently introduced on the Greek market and it has become a hot topic that has generated global debate with the authorities. The aim of this review is to explain what the e-cigarette is and to examine its safety and efficacy in smoking cessation or reduction.
The authors declare no conflict of interest.
Centers for Disease Control and Prevention (CDC). Smokingattributable mortality, years of potential life lost, and productivity losses--United States, 2000-2004. MMWR Morb Mortal Wkly Rep 2008; 57:1226-1228.
Centers for Disease Control and Prevention (CDC). Cigarette smoking among adults and trends in smoking cessation - United States, 2008. MMWR Morb Mortal Wkly Rep 2009; 58:1227-1232.
Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ 2004; 328:1519.
Anthonisen NR, Skeans MA, Wise RA, Manfreda J, Kanner RE, Connett JE; Lung Health Study Research Group. The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med 2005; 142:233-239.
Rigotti NA. Clinical practice. Treatment of tobacco use and dependence. N Engl J Med 2002; 346:506-512.
Henningfield JE, Miyasato K, Jasinski DR. Abuse liability and pharmacodynamic characteristics of intravenous and inhaled nicotine. J Pharmacol Exp Ther 1985; 234:1-12.
2008 PHS Guideline Update Panel, Liaisons, and Staff. Treating tobacco use and dependence: 2008 update U.S. Public Health Service Clinical Practice Guideline executive summary. Respir Care 2008; 53:1217-1222.
WHO Study Group on Tobacco Production Regulation. WHO Study Group on Tobacco Product Regulation. Report on the scientific basis of tobacco product regulation: third report of a WHO Study Group. World Health Organ Tech Rep Ser 2009; 955:1-41.
H-Plus. [cited 2011 Jul 10]. Available from
Civljak M, Sheikh A, Stead LF, Car J. Internet-based interventions for smoking cessation. Cochrane Database Syst Rev 2010;9:CD007078.
Thomsen T, Villebro N, Muller AM. Interventions for preoperative smoking cessation. Cochrane Database Syst Rev 2010;7:CD002294.
Vardavas CI, Anagnostopoulos N, Kougias M, Evangelopoulou V, Connolly GN, Behrakis PK. Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impedance, and exhaled nitric oxide. Chest 2012;141:1400-1406.
Westenberger BJ. US Food and Drug Administration evaluation of e-cigarettes. Center for Drug Evaluation and Research, Division of Pharmaceutical Analysis. Rockville, MD: US Food and Drug Administration, 2009.
Laugesen M. Safety report on the Ruyan e-cigarette cartridge and inhaled aerosol. Christchurch, New Zealand: Health New Zealand Ltd; 2008.
Cahn Z, Siegel M. Electronic cigarettes as a harm reduction strategy for tobacco control: A step forward or a repeat of past mistakes? J Public Health Policy 2011; 32:16-31.
Etter JF. Electronic cigarettes: a survey of users. BMC Public Health 2010; 10:231.
European Respiratory Society statement on E-cigarettes and emerging products. (February 2012).
WHO: Marketers of electronic cigarettes should halt unproved therapy claims. 2008 Geneva, World Health Organization
Bullen C, McRobbie H, Thornley S, Glover M, Lin R, Laugesen M. Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial. Tob Control 2010;19:98–103.
Polosa R, Caponnetto P, Morjaria JB, Papale G, Campagna D, Russo C. Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study. BMC Public Health 2011; 11:786.
Trtchounian A, Williams M, Talbot P. Conventional and electronic cigarettes (e-cigarettes) have different smoking characteristics. Nicotine Tob Res 2010; 12:905–912.
Etter JF, Bullen C. Electronic cigarette: users profile, utilization, satisfaction and perceived efficacy. Addiction 2011; 106:2017- 2028.
US Surgeon General (2003)
Journals System - logo
Scroll to top