Smoking and pregnancy
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National and Kapodistrian University of Athens, Medical Faculty. Hellenic Cancer Society, Research Centre for Smoking and Lung Cancer, sponsorship from George D. Behrakis
Adjunct Associate Professor of Physiology, Department of Environmental Health, School of Public Health, Harvard University
Corresponding author
Andriani Loukopoulou   

V. Othonos 65, Kifisia, 14561 Attiki
Pneumon 2010;23(2):160-167
Maternal smoking during pregnancy is considered to be one of the most significant causes of complications in pregnancy and is associated with an unfavourable outcome in childbirth compared with pregnancy in non-smokers. Specifically, smoking during pregnancy increases the likelihood of placenta praevia, abruptio placentae, ectopic gestation and premature rupture of the membranes (PRM). In addition, research has established that smoking during pregnancy increases the rates of low birth weight (LBW), perinatal mortality, premature birth and sudden infant death syndrome (SIDS). As these children grow up they present a variety of health problems, including respiratory illness, behaviour disturbances, attention deficit hyperactivity disorder (ADHD) and high arterial blood pressure. LBW is also associated with an increased incidence of health problems in the neonatal period. Effects have been documented of maternal smoking during pregnancy on the future fertility of male infants and the occurrence of congenital abnormalities, and a connection has been reported between daily maternal smoking in early pregnancy and infantile autism.
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