Pneumocystis jirovecii Pneumonia Prophylaxis in non-HIV pulmonary patients on chronic corticosteroid therapy: make a virtue of necessity?
More details
Hide details
7th Pulmonary Department, Athens Chest Hospital, Greece
2nd Department of Pneumonology, Medical School, National and Kapodistrian University of Athens, Greece
1st Department of Pneumonology, Medical School, National and Kapodistrian University of Athens, Greece
Corresponding author
Demosthenes Bouros   

1st Department of Pneumonology, Hospital for Diseases of the Chest “SOTIRIA”, Medical School, National and Kapodistrian University of Athens, Messogion 152, Athens 11527, Greece
Pneumon 2015;28(1):28-30
All the authors declare that they do not have a financial relationship with a commercial entity that has an interest in the subject of this manuscript.
Catherinot E, Lanternier F, Bougnoux ME, Lecuit M, Couderc LJ, Lortholary O. Pneumocystis jirovecii Pneumonia. Infect Dis Clin North Am 2010;24:107-138.
Pneumocystis Pneumonia. 3rd ed, Walzer PD, Cushion MT (Ed), Marcel Decker, New York 2005.
Yale SH, Limper AH. Pneumocystis carinii pneumonia in patients without acquired immunodeficiency syndrome: associated illness and prior corticosteroid therapy. Mayo Clin Proc 1996;71:5-13.
Rano A, Agusti C. Pulmonary infections in patients on chronic glucocorticoid treatment. In: Pulmonary infection in the immunocompromised patient: Strategies for management. Agusti C, Torres A (Ed), John Wiley & Sons, 2009.
Plakke MJ, Jalota L, Lloyd BJ. Pneumocystis pneumonia in a non-HIV patient on chronic corticosteroid therapy: a question of prophylaxis. BMJ Case Rep 2013;doi: 10.1136/bcr-2012-007912.
Gripaldo R, Lippmann ML. Pneumocystis pneumonia in HIVnegative patients: a review of the literature. Clin Pulm Med 2012;19:5-13.
Festic E, Gajic O, Limper AH, et al. Acute respiratory failure due to pneumocystis pneumonia in patients without human immunodeficiency virus infection: outcome and associated features. Chest 2005;128:573-579.
Sing A, Roggenkamp A, Autenrieth IB, et al. Pneumocystis carinii carriage in immunocompetent patients with primary pulmonary disorders as detected by single or nested PCR. J Clin Microbiol 1999;37:3409-3410.
Vidal S, de la Horra C, Martin J, et al. Pneumocystis jirovecii colonisation in patients with interstitial lung disease. Clin Microbiol Infect 2006;12:231-235.
Mori S, Cho I, Ichiyasu H, et al. Asymptomatic carriage of Pneumocystis jiroveci in elderly patients with rheumatoid arthritis in Japan: a possible association between colonization and development of Pneumocystis jiroveci pneumonia during low-dose MTX therapy. Mod Rheumatol 2008;18:240-246.
Wissmann G, Varela JM, Calderon EJ. Prevention of Pneumocystis pneumonia in patients with inflammatory bowel disease based on the detection of Pneumocystis colonization. Inflamm Bowel Dis 2008;14:1751-1752.
Thomas CF Jr, Limper AH. Current insights into the biology and pathogenesis of Pneumocystis pneumonia. Nat Rev Microbiol 2007;5:298-308.
Bhagwat SP, Gigliotti F, Xu H, et al. Contribution of T cell subsets to the pathophysiology of Pneumocystis-related immunorestitution disease. Am J Physiol Lung Cell Mol Physiol 2006;291:L1256-1266.
Arend SM, Kroon FP, van’t Wout JW. Pneumocystis carinii pneumonia in patients without AIDS, 1980 through 1993. An analysis of 78 cases. Arch Intern Med 1995;155:2436-2441.
Gluck T, Geerdes-Fenge HF, Straub RH, et al. Pneumocystis carinii pneumonia as a complication of immunosuppressive therapy. Infection 2000;28:227-230.
Enomoto T, Azuma A, Matsumoto A, et al. Preventive effect of sulfamethoxasole-trimethoprim on Pneumocystis jiroveci pneumonia in patients with interstitial pneumonia. Intern Med 2008;47:15-20.
Kim SJ, Lee J, Cho YJ, et al. Prognostic factors of Pneumocystis jirovecii pneumonia in patients without HIV infection. J Infect 2014;69:88-95.
Limper AH, Knox KS, Sarosi GA, et al; American Thoracic Society Fungal Working Group. An official American Thoracic Society statement: Treatment of fungal infections in adult pulmonary and critical care patients. Am J Respir Crit Care Med 2011;183:96-128.
Stern A, Green H, Paul M, Vidal L, Leibovici L. Prophylaxis for Pneumocystis pneumonia (PCP) in non-HIV immunocompromised patients. Cochrane Database Syst Rev 2014;10:doi: 10.1002/14651858.
Journals System - logo
Scroll to top