Hypercoagulability in obstructive sleep apnea syndrome
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Medical School, Democritus University of Thrace, Alexandroupolis, Greece
Publication date: 2021-06-17
Corresponding author
Paschalis Steiropoulos   

Medical School, Democritus University of Thrace Dragana 68100, Alexandroupolis, Greece
Pneumon 2016;29(1):22-26
Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive episodes of upper airway obstruction, leading to intermittent hypoxia, hypercapnia and increased sympathetic nervous system activity and proposed to induce platelet activation. Additionally, OSAS has been linked to increased cardiovascular mortality and morbidity. Blood coagulation abnormalities have been suggested to play a fundamental role in increased cardiovascular risk in OSAS patients. The aim of the present review was to summarize the current evidence that revealed the pathogenetic alterations in blood coagulation in patients with OSAS.
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