Endobronchial Involvement in Miliary Tuberculosis
More details
Hide details
Pneumonology Diseases Department, Cerrahpasa Medical Faculty, Istanbul University
Pathology Department, Taksim Research and Training Hospital, Istanbul, Turkey
Corresponding author
Cuneyt Tetikkurt   

Tanzimat sok. Serkan Apt No 8/16 Caddebostan, 34728, Istanbul, Turkey
Pneumon 2010;23(2):135-140
Endobronchial tuberculosis (EBTB) is the tuberculous infection of the tracheobronchial tree. It has been reported in patients with parenchymal infiltrations and cavities in the lung and intrathoracic tuberculous lymphadenopathy. The occurrence of bronchial lesions in miliary tuberculosis is most likely to be a result of hematogenous dissemination of tubercle bacilli. We report six patients with endobronchial involvement in miliary tuberculosis. Bronchoscopic examination with histopathological evidence is essential to exclude or confirm endobronchial involvement in miliary tuberculosis. Chest computed tomography (CT) may be a useful diagnostic adjunct for evaluating bronchial stenosis, but does not show the mucosal changes of endobronchial inflammation if the lesions are superficial or mild. Local steroid injection appears to be useful for the treatment of superficial mucosal lesions involving less than one quarter of the bronchial lumen, but for advanced inflammatory lesions local treatment is ineffective. Local steroid injection for the treatment of bronchial narrowing is contraindicated by the finding of significant bronchial or segmental stenosis on CT scan. The evolution of airway involvement in miliary tuberculosis indicates that hematogenous dissemination of the bacilli is the primary mechanism for endobronchial tuberculosis.
Han JK, Im JG, Park JH, et all. Bronchial stenosis due to endobronchial tuberculosis: Successful treatment with self-expanding metallic stent. Am J Roentgenol 1992; 159: 971-972.
Chang SC, Lee PY, Pernig RP. Clinical role of bronchoscopy in adults with intrathoracic tuberculous lymphadenopathy. Chest 1988; 93: 314-317.
Lee JH, Park SS, Lee DH, et all. Endobronchial tuberculosis. Clinical and bronchoscopic features in 121 cases. Chest 1992; 102: 990-992.
An JY, Lee JE, Park HW, et all. Clinical and bronchoscopic features in endobronchial tuberculosis. Tuberc Respir Dis 2006; 60: 532-539.
Smart J. Endobronchial tuberculosis. Br J Dis Chest 1951; 45: 61-68.
Sahn SA, Neff TA. Miliary tuberculosis. Am J Med 1974; 56: 495-505.
Geppert EF, Leff A. The pathogenesis of pulmonary and miliary tuberculosis. Arch Intern Med 1979; 139: 1381-1383.
Murray HW, Tuazon CU. Kirmani N, et all. The adult respiratory distress syndrome associated with miliary tuberculosis. Chest 1979; 73: 37-43.
Dhillon. SS, Hanania NA. Endobronchial tuberculosis. In: Sharma SK (ed). New Delhi, Jaypee Brothers Medical Publishers, 2009: 232-244.
Williams DJ, York EL, Nobert EJ, et all. Endobronchial tuberculosis presenting as asthma. Chest 1988; 93: 836-838.
Matthews JI, Matarese SL, Carpenter JL. Endobronchial tuberculosis simulating lung cancer. Chest 1984; 86: 642-644.
Yanardag H, Tetikkurt C, Tetikkurt S, et all. Computed tomography and bronchoscopy in endobronchial tuberculosis. Can Respir J 2003; 10(8): 445-448.
Journals System - logo
Scroll to top