ORIGINAL PAPER
Endobronchial Involvement in Miliary Tuberculosis
			
	
 
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				1
				Pneumonology Diseases Department, Cerrahpasa Medical Faculty, Istanbul University
				 
			 
						
				2
				Pathology Department, Taksim Research and Training Hospital, Istanbul, Turkey
				 
			 
										
				
				
		
		 
			
			
		
		
		
		
		
		
	
							
					    		
    			 
    			
    				    					Corresponding author
    					    				    				
    					Cuneyt  Tetikkurt   
    					Tanzimat sok. Serkan Apt No 8/16
Caddebostan, 34728, Istanbul, Turkey
    				
 
    			
				 
    			 
    		 		
			
																						 
		
	 
		
 
 
Pneumon 2010;23(2):135-140
 
 
KEYWORDS
ABSTRACT
Endobronchial tuberculosis (EBTB) is the tuberculous infection of the tracheobronchial tree. It has been reported in patients with parenchymal infiltrations and cavities in the lung and intrathoracic tuberculous lymphadenopathy. The occurrence of bronchial lesions in miliary tuberculosis is most likely to be a result of hematogenous dissemination of tubercle bacilli. We report six patients with endobronchial involvement in miliary tuberculosis. Bronchoscopic examination with histopathological evidence is essential to exclude or confirm endobronchial involvement in miliary tuberculosis. Chest computed tomography (CT) may be a useful diagnostic adjunct for evaluating bronchial stenosis, but does not show the mucosal changes of endobronchial inflammation if the lesions are superficial or mild. Local steroid injection appears to be useful for the treatment of superficial mucosal lesions involving less than one quarter of the bronchial lumen, but for advanced inflammatory lesions local treatment is ineffective. Local steroid injection for the treatment of bronchial narrowing is contraindicated by the finding of significant bronchial or segmental stenosis on CT scan. The evolution of airway involvement in miliary tuberculosis indicates that hematogenous dissemination of the bacilli is the primary mechanism for endobronchial tuberculosis.
		
	
		
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