Bronchiectasis and Emphysema
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Pulmonologist, Director of 5th Pulmonary department, “Sotiria” Chest Hospital, Athens, Greece
Pulmonologist, 5th Pulmonary department, “Sotiria” Chest Hospital, Athens, Greece
Pulmonologist, 6th Pulmonary department, “Sotiria” Chest Hospital, Athens, Greece
Corresponding author
Katerina Dimakou   

152 Mesogion Ave., 11527 Athens, Greece
Pneumon 2016;29(4):334-337
Emphysema is the predominant component in alpha1-Antitrypsin (α1-AT) Deficiency, but the prevalence and impact of bronchiectasis is greater than previously recognized. Bronchiectasis is more common and severe where emphysema is seen and may add to the severity of the disease and worse health status. The pathogenetic association between bronchiectasis and emphysema is not well defined. Whether bronchiectasis take advantage of the α1-AT augmentation therapy remains unknown. The coexistence of emphysema and bronchiectasis in COPD patients is nor rare. Bronchiectasis could have an impact on disease course over and above the effects of emphysema. From the other side, the presence of emphysema in bronchiectasis is common and may contribute to the severity of airways obstruction. Emphysema may represent a risk factor of mortality in patients with bronchiectasis.
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