REVIEW
The use of mandibular advancement devices for the treatment of Obstructive Sleep Apnea
 
More details
Hide details
1
Orthodontist, Department of Pneumonology Medicine, University Hospital of Patras, Patras, Greece
 
2
Department of Pneumonology Medicine, University Hospital of Patras, Patras, Greece
 
3
Guy’s and St Thomas’ Hospital, Sleep Disorders Centre, London, United Kingdom
 
 
Corresponding author
Kostas Spiropoulos   

Pneumonology Medicine, University of Patras, Patras 26500, Greece
 
 
Pneumon 2016;29(2):147-151
 
KEYWORDS
ABSTRACT
Obstructive Sleep Apnea (OSA) is the most common type of sleep disordered breathing, having numerous systematic consequences. Continuous Positive Airway Pressure devices (CPAP) have been used effectively so far for the treatment of OSA, but there is an important number of patients, up to 50%, that show bad adherence to CPAP treatment and may finally quit. Other therapeutic interventions that have been effective are dental devices that force the mandible to a forward position. The placement of these so called mandibular advancement devices (Mandibular Advancement Devices/MADs) causes the mandible to be positioned forward and downwards to its normal position. These dental devices are an acceptable option for the treatment of OSA apart from CPAP. Although, their efficacy is lower than that of CPAP in severe OSA, they can be effectively used in mild to moderate OSA because of their ease of use, lower cost and because they can be well-tolerated.
 
REFERENCES (27)
1.
Sherring D, Vowles N, Antic R, Krishnan S, Goss A. Obstructive sleep apnoea: a review of the orofacial implications. Aust Dent J 2001; 46:154-65.
 
2.
Ronchi P, Cinquini V, Ambrosoli A, Caprioglio A. Maxillomandibular advancement in obstructive sleep apnea syndrome patients: a restrospective study on the sagittal cephalometric variables. J Oral Maxillofac Res 2013; 1;4(2).
 
3.
Lykouras D, Theodoropoulos K, Sampsonas F, et al. The impact of obstructive sleep apnea syndrome on renin and aldosterone. Eur Rev Med Pharmacol Sci 2015; 19:4164-70.
 
4.
Peppard PE, Young T, Barnet JH, et al. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 2013;177:1006-14.
 
5.
Strollo P, Rogers R. Obstructive sleep apnea. N Eng J Med 1996; 334:99-104.
 
6.
American Academy of Sleep Medicine. International classification of sleep disorders 3rd ed. Darien, IL: s.n., 2014.
 
7.
Ramar K, Dort L, Katz S, et al. Clinical Practice Guideline for the Treatment of Obstructive Sleep Apnea and Snoring with Oral Appliance Therapy: An Update for 2015. J Clin Sleep Med 2015; 11:773-827.
 
8.
Berry R, Camaldo C, Harding S, Marcus C, Vaughn B. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.0. Darien, Illinois: American Academy of Sleep Medicine, 2012.
 
9.
Cartwright R. Effect of sleep position on sleep apnoea severity. Sleep 1984; 7:110-4.
 
10.
Smith P, Gold A, Myer D. Weight loss in mild to moderately obese patients with obstructive sleep apnoea. Ann Intern Med 1985; 105:850-61.
 
11.
Karkoulias K, Lykouras D, Sampsonas F, et al. The impact of obstructive sleep apnea syndrome severity on physical performance and mental health. The use of SF-36 questionnaire in sleep apnea. Eur Rev Med Pharmacol Sci 2013; 17:531-6.
 
12.
Epstein L, Kristo D, Strollo P, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 2009; 5:263-76.
 
13.
Vanderveken O, Devolder A, Marklund M, et al. Comparison of a custom-made and a thermoplastic oral appliance for the treatment of mild sleep apnea. Am J Respir Crit Care Med 2008; 178:197–202.
 
14.
Kato J, Isono S, Tanaka A, et al. Dose-dependent effects of mandibular advancement on pharyngeal mechanics and nocturnal oxygenation in patients with sleep-disordered breathing. Chest 2000; 117:1065-72.
 
15.
Walker-Engstrom M, Ringqvist I, Vestling O, Wilhelmsson B, Tegelberg A. A prospective randomized study comparing two different degrees of mandibular advancement with a dental appliance in treatment of severe obstructive sleep apnea. Sleep Breath 2003; 7:119-30.
 
16.
Pitsis A, Darendeliler M, Gotsopoulos H, Petocz P, Cistulli P. Effect of vertical dimension on efficacy of oral appliance therapy in obstructive sleep apnea. Am J Respir Crit Care Med 2002; 166:860-4.
 
17.
Ryan C, Love L, Peat D, Fleetham J, Lowe A. Mandibular advancement oral appliance therapy for obstructive sleep apnoea: effect on awake calibre of the velopharynx. Thorax 1999; 54:972-7.
 
18.
Sutherland K, Vanderveken O, Tsuda H, et al. Oral appliance treatment for obstructive sleep apnea: an update. J Clin Sleep Med 2014; 10:215–27.
 
19.
Andren A, Hedberg P, Walker-Engstrom M, Wahlen P, Tegelberg A. Effects of treatment with oral appliance on 24-h blood pressure in patients with obstructivesleep apnea and hypertension: a randomized clinical trial. Sleep Breath 2013; 17:705-12.
 
20.
Blanco J, Zamarron C, Abeleira Pazos M, Lamela C, Suarez Quintanilla D. Prospective evaluation of an oral appliance in the treatment of obstructive sleepapnea syndrome. Sleep Breath 2005; 9:20-5.
 
21.
Hans M, Nelson S, Luks V, Lorkovich P, Baek S. Comparison of two dentaldevices for treatment of obstructive sleep apnea syndrome (OSAS). Am J Orthod Dentofacial Orthop 1997; 111:562-70.
 
22.
Petri N, Svanholt P, Solow B, Wildschiodtz G, Winkel P. Mandibular advancement appliance for obstructive sleep apnoea: results of a randomised placebocontrolled trial using parallel group design. J Sleep Res 2008; 17:221-9.
 
23.
Brette C, Ramanantsoa H, Renouardiere J, Renouardiere R, Roisman G, Escourrou P. A mandibular advancement device for the treatment of obstructive sleep apnea: long-term use and tolerance. Int Orthod 2012; 10:363-76.
 
24.
Phillips C, Grunstein R, Darendeliler M, et al. Health outcomes of continuous positive airway pressure versus oral appliance treatment for obstructive sleep apnea: a randomized controlled trial. Am J Respir Crit Care Med 2013; 187:879-87.
 
25.
American Sleep Disorders Association. Practice parameters for the treatment of snoring and obstructive sleep apnea with oral appliances. Sleep 1995; 18:511–513.
 
26.
Prescinotto R, Haddad FL, Fukuchi I, et al. Impact of upper airway abnormalities on the success and adherence to mandibular advancement device treatment in patients with Obstructive Sleep Apnea Syndrome. Braz J Otorhinolaryngol 2015; 81:663- 70.
 
27.
Pliska B, Nam H, Chen H, Lowe A, Almeida F. Obstructive sleep apnea and mandibular advancement splints: occlusal effects and progression of changes associated with a decade of treatment. J Clin Sleep Med 2014; 10:1285-91.
 
eISSN:1791-4914
ISSN:1105-848X
Journals System - logo
Scroll to top