EDITORIAL
The toll of ozone
 
More details
Hide details
1
Center for Host Defense, Inflammation, and Lung Disease CHILD Research, Department of Pediatrics
2
Obstetrics and Gynecology, Pennsylvania State University College of Medicine, Hershey, PA 17033
CORRESPONDING AUTHOR
Joanna Floros   

Pediatrics and Obstetrics & Gynecology, CHILD Research Dept of Pediatrics 500 University Drive, H085 Hershey, PA 17033
 
Pneumon 2011;24(1):20–23
 
ACKNOWLEDGEMENTS
This work was supported by National Institute of Environmental Health Sciences Grant 1RO1-ES09882.
 
REFERENCES (46)
1.
Siafakas N. The Year of the Lung 2010. Pneumon 2010;23:336- 337.
 
2.
Ground-level ozone in the 21st Century: future trends, impacts and policy implications: Science Policy Report 15/08 for the Royal Society; 2008.
 
3.
Fishman J, Wozniak AE, Creilson JK. Global distribution of tropospheric ozone from satellite measurements using the empirically corrected tropospheric ozone residual technique: Identification of the regional aspects of air pollution. Atmos Chem Phys 07/02 2003;3:893-907.
 
4.
Vingarzan R. A review of surface ozone background levels and trends. Atmospheric Environment 2004;38:3431-3442.
 
5.
Ozone Air Quality 1980-2008. Available at http://www.epa.gov/airtrends/o....
 
6.
Pennsylvania Air Quality Monitoring 2004 Annual Report: Pennsylvania Department of Environmental Protection. Available at http://www.depweb.state.pa.us/
 
7.
Ozone Air Quality 1990-2008. Available at http://www.epa.gov/cgi-bin/bro....
 
8.
Ambient Air Quality Standards. Available at http://www.depweb/
 
9.
EPA Proposes a Stronger Ozone Standard: American Lung Association January 2010.
 
10.
Pinkerton. Ozone, a malady for all ages. Am J Respir Care Med 2007;176:107-112.
 
11.
EPA report provides an assessment of potential impacts of climate change on US regional ozone concentrations. Science in Action. April 2009. Available at http://www.epa.gov/ord
 
12.
Weaver CP, Cooter E, Gilliam R, et al. A Preliminary Synthesis of Modeled Climate Change Impacts on U.S. Regional Ozone Concentrations. Bulletin of the American Meteorological Society 2009;90:1843-1863.
 
13.
Nolte CG, Gilliland AB, Hogrefe C, Mickley LJ. Linking global to regional models to assess future climate impacts on surface ozone levels in the United States. J Geophys Res 07/22 2008;113(D14):D14307.
 
14.
Ebi KL, McGregor G. Climate change, tropospheric ozone and particulate matter, and health impacts. Environ Health Perspect 2008;116:1449-1455.
 
15.
Thomson MC. Seasonal Forecasts, Climatic Change and Human Health: Health and Climate New York: Springer; 2008.
 
16.
Ozone and your patients’ health, training for health care providers. Available at www.epa/gov/air/oaqps/eog/ozon....
 
17.
Schelegle ES, Morales CA, Walby WF, Marion S, Allen RP. 6.6- hour inhalation of ozone concentrations from 60 to 87 parts per billion in healthy humans. Am J Respir Crit Care Med 2009;180:265-272.
 
18.
Kunzili N, Perez L, Rapp R. Air Quality and Health. In: Soc ER, ed. 2010 The year of the Lung; 2010.
 
19.
Protecting your health. Air Quality Partnership. Available at http://www.aqpartners.state.pa...
 
20.
Alexeeff SE, Litonjua AA, Wright RO, et al. Ozone exposure, antioxidant genes, and lung function in an elderly cohort: VA normative aging study. Occup Environ Med 2008;65:736-742.
 
21.
Kan H, London SJ, Chen G, et al. Season, sex, age, and education as modifiers of the effects of outdoor air pollution on daily mortality in Shanghai, China: The Public Health and Air Pollution in Asia (PAPA) Study. Environ Health Perspect 2008;116:1183-1188.
 
22.
Medina-Ramon M, Schwartz J. Who is more vulnerable to die from ozone air pollution? Epidemiology 2008;19:672-679.
 
23.
Vancza EM, Galdanes K, Gunnison A, Hatch G, Gordon T. Age, strain, and gender as factors for increased sensitivity of the mouse lung to inhaled ozone. Toxicol Sci 2009;107:535-543.
 
24.
Stafoggia M, Forastiere F, Faustini A, et al. Susceptibility factors to ozone-related mortality: a population-based case-crossover analysis. Am J Respir Crit Care Med 2010;182:376-384.
 
25.
Salam MT, Millstein J, Li YF, Lurmann FW, Margolis HG, Gilliland FD. Birth outcomes and prenatal exposure to ozone, carbon monoxide, and particulate matter: results from the Children’s Health Study. Environ Health Perspect 2005;113:1638-1644.
 
26.
Hwang BF, Jaakkola JJ. Ozone and other air pollutants and the risk of oral clefts. Environ Health Perspect 2008;116:1411-1415.
 
27.
Smoggy Schools. Environmental Working Group. 04/20/2005; Available at http://ewg.org/reports/caschoo....
 
28.
Henrotin JB, Besancenot JP, Bejot Y, Giroud M. Short-term effects of ozone air pollution on ischaemic stroke occurrence: a case-crossover analysis from a 10-year population-based study in Dijon, France. Occup Environ Med 2007;64:439-445.
 
29.
Lang JE, Williams ES, Mizgerd JP, Shore SA. Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6. Am J Physiol Lung Cell Mol Physiol 2008;294:L1013-1020.
 
30.
Alexeeff SE, Litonjua AA, Suh H, Sparrow D, Vokonas PS, Schwartz J. Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study. Chest 2007;132:1890-1897.
 
31.
Lin S, Liu X, Le LH, Hwang SA. Chronic exposure to ambient ozone and asthma hospital admissions among children. Environ Health Perspect 2008;116:1725-1730.
 
32.
Moore K, Neugebauer R, Lurmann F, et al. Ambient ozone concentrations cause increased hospitalizations for asthma in children: an 18-year study in Southern California. Environ Health Perspect 2008;116:1063-1070.
 
33.
Medina-Ramon M, Zanobetti A, Schwartz J. The effect of ozone and PM10 on hospital admissions for pneumonia and chronic obstructive pulmonary disease: a national multicity study. Am J Epidemiol 15 2006;163:579-588.
 
34.
Chiu HF, Cheng MH, Yang CY. Air pollution and hospital admissions for pneumonia in a subtropical city: Taipei, Taiwan. Inhal Toxicol 2009;21:32-37.
 
35.
Bascom R, Bromberg PA, Costa DA, et al. Health effects of outdoor air pollution. Committee of the Environmental and Occupational Health Assembly of the American Thoracic Society. Am J Respir Crit Care Med 1996;153:3-50.
 
36.
Zanobetti A, Schwartz J. Mortality displacement in the association of ozone with mortality: an analysis of 48 cities in the United States. Am J Respir Crit Care Med 2008;177:184-189.
 
37.
Stieb D, Szyszkowicz M, Rowe B, Leech J. Air pollution and emergency department visits for cardiac and respiratory conditions: a multi-city time-series analysis. Environmental Health 2009;8:25.
 
38.
Jerrett M, Burnett RT, Pope CA, et al. Long-term ozone exposure and mortality. N Engl J Med 2009;360:1085-1095.
 
39.
Horstman DH, Folinsbee LJ, Ives PJ, Abdul-Salaam S, McDonnell WF. Ozone concentration and pulmonary response relationships for 6.6-hour exposures with five hours of moderate exercise to 0.08, 0.10, and 0.12 ppm. Am Rev Respir Dis 1990;142:1158- 1163.
 
40.
Devlin RB, McDonnell WF, Mann R, et al. Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am J Respir Cell Mol Biol 1991;4:72-81.
 
41.
Kulle TJ, Sauder LR, Hebel JR, Chatham MD. Ozone response relationships in healthy nonsmokers. Am Rev Respir Dis 1985;132:36-41.
 
42.
Kleeberger SR, Bassett DJ, Jakab GJ, Levitt RC. A genetic model for evaluation of susceptibility to ozone-induced inflammation. Am J Physiol 1990;258(6 Pt 1):L313-320.
 
43.
Wesselkamper SC, Prows DR, Biswas P, Willeke K, Bingham E, Leikauf GD. Genetic susceptibility to irritant-induced acute lung injury in mice. Am J Physiol Lung Cell Mol Physiol 2000;279:L575- 582.
 
44.
Romley JA, Hackbarth A, Goldman DP. The Impact of Air Quality on Hospital Spending. Santa Monica, CA: RAND Corporation; 2010.
 
45.
Selin NE, Wu S, Nam K-M, et al. Global health and economic impacts of future ozone pollution. Environmental Research Letters 2009;4.
 
46.
Nam K-M, Selin NE, Reilly JM, Paltsev S. Measuring welfare loss caused by air pollution in Europe: A CGE analysis. Energy Policy 2009;38:5059-5071.
 
eISSN:1791-4914
ISSN:1105-848X