Home
Issues
Aim & Scope
Open Access
Indexing
Why publish with us
Contact
Editorial Board
Instructions to Authors (PDF)
Manuscript Types
Manuscript Formatting
How to submit
Preprints
Authorship & COI
Principles of Transparency Checklist
Publication Ethics and Publication Malpractice Statement
CrossMark
Data Policies
EDITORIAL
The Immunology of pulmonary fibrosis: The role of Th1/Th2/Th17/Treg cells
1
Medical School, Democritus University of Thrace, Alexandroupolis, Greece
2
Professor of Pneumonology, Deptartment of Pneumonology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece
Corresponding author
Demosthenes Bouros
Dept of Pneumonology, Dept of Internal Medicine, University Hospital of Alexandroupolis Alexandroupolis, Greece, 68100
Dept of Pneumonology, Dept of Internal Medicine, University Hospital of Alexandroupolis Alexandroupolis, Greece, 68100
Pneumon 2010;23(1):17-20
REFERENCES (18)
1.
Gross TJ, Hunninghake GW Idiopathic pulmonary fibrosis. N Engl J Med 2001;345:517-525.
2.
Strieter RM Pathogenesis and natural history of usual interstitial pneumonia: the whole story or the last chapter of a long novel. Chest 2005;128:526S-532S.
3.
Agostini C, Gurrieri C. Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis. Proc Am Thorac Soc 2006;3:357-363.
4.
Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med 2007;13:139-145.
5.
Joshi AD, Fong DJ, Oak SR, et al. Interleukin-17-mediated immunopathogenesis in experimental hypersensitivity pneumonitis. Am J Respir Crit Care Med 2009;179:705-716.
6.
Simonian PL, Roark CL, Wehrmann F, et al. Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis. J Immunol 2009;182:657-665.
7.
Belghith M, Bluestone JA, Barriot S, Megret J, Bach JF. Chatenoud L TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 2003;9:1202-1208.
8.
Bettelli E, Carrier Y, Gaoet W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441:235-238.
9.
Huang MC, Liao JJ, Bonasera S, Longo DL, Goetzl EJ. Nuclear factor-kappaB-dependent reversal of aging-induced alterations in T cell cytokines. FASEB J 2008;22:2142-2150.
10.
O'Garra A, Vieira P. Regulatory T cells and mechanisms of immune system control. Nat Med 2004;10:801-805.
11.
Kearley J, Buckland KF, Mathie SA, Lloyd CM. Resolution of alergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway. Am J Respir Crit Care Med 2009;179:772-781.
12.
Feghali-Bostwick CA, Tsai CG, Valentine VG, et al. Cellular and humoral autoreactivity in idiopathic pulmonary fibrosis. J Immunol 2007;179:2592-2599.
13.
Miyara M, Amoura Z, Parizot C, et al, Chapelon-Abric, P. Debre, J. C. Piette, and G. Gorochov. The immune paradox of sarcoidosis and regulatory T cells. J Exp Med 2006;203:359-370.
14.
Grunewald J, Eklund A. Role of CD4+ T cells in sarcoidosis. Proc Am Thorac Soc 2007;4:461-464.
15.
Kotsianidis I, Nakou E, Bouchliou I, et al. Global impairment of CD4+CD25+FOXP3+ regulatory T cells in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2009;179:1121-1130.
16.
D'Alessio FR, Tsushima K, Aggarwal NR, et al. CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury. J Clin Invest 2009;119:2898- 2913.
17.
Mark AAC, de Knegt RJ, Tilanus HW et al. Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis. J Hepatol 2010;52:315-321.
18.
Bouros D. Sexy and 17: Two novel pathways in immune regulation. Pneumon 2009;19:216-218.
| eISSN: | 1791-4914 |
| ISSN: | 1105-848X |
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
